On which chromosome is Severe Combined Immunodeficiency located?

Severe Combined Immunodeficiency (SCID) is a genetic disorder that affects the immune system, leading to severe vulnerabilities to infections. The most common form of SCID, X-linked SCID, is caused by a mutation in the IL2RG gene, which is located on the X chromosome, not on chromosome 20. However, there are other forms of SCID, such as adenosine deaminase deficiency (ADA-SCID), which is associated with mutations on chromosome 20.

Given that you selected chromosome 20 as the location for SCID, it is pertinent to note that while many genetic conditions have multiple underlying genetic causes, ADA-SCID indeed affects chromosome 20. This highlights the complexity of genetic disorders, where different types can arise from mutations on various chromosomes. Understanding this genetic variability is important for accurately diagnosing and treating these conditions.